Decoding host and pathogen co-evolution in humans and non-human primates.

Pathogens and hosts exert strong selective pressures on each other, leading to some of the most striking patterns of genetic variation across populations today.

We are studying the ongoing evolutionary battle between primate hosts and their pathogens, with special focus on longstanding interactions with malaria parasites. We apply computational approaches to both pathogen and primate population genomic datasets from community samples and infections to learn about the evolution of their molecular interface.

Ellen Leffler

Assistant Professor of Human Genetics